- Charles F. Kettering, Ohio State '04, founder of the Sloan-Kettering Institute for cancer research
- Laurens Hammond, Cornell '16, inventor of the pipeless organ
- Arnold O. Beckman, Illinois '22, Inventor of the pH meter and founder of Beckman Instruments
- Linus C. Pauling, Oregon State '22, winner of two Nobel Prizes ; chemistry and peace
- Dr. Christian Boehmer Anfinsen, Jr., Swarthmore '37, Nobel Prize winner for chemistry
- Dr. Augustus A. White, III, Brown '57, Chief Surgeon of Orthopaedics at Beth Israel Hospital in Boston
- Col. Frederick R. Hauck, Tufts '62, NASA astronaut
- Brewster H. Shaw, Wisconsin '67, NASA astronaut
- Terry Hart, Lehigh '68, NASA astronaut
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